The Austroasiatic Munda Population from India and Its Enigmatic Origin: A HLA Diversity Study

@inproceedings{Riccio2011TheAM,
  title={The Austroasiatic Munda Population from India and Its Enigmatic Origin: A HLA Diversity Study},
  author={Mar{\'i}a Eugenia Riccio and Jos{\'e} Manuel Nunes and M Rahal and Barbara Kervaire and Jean Marie Tiercy and Alicia Sanchez‐Mazas},
  booktitle={Human biology},
  year={2011}
}
Abstract The Austroasiatic linguistic family disputes its origin between two geographically distant regions of Asia, India, and Southeast Asia, respectively. As genetic studies based on classical and gender-specific genetic markers provided contradictory results to this debate thus far, we investigated the HLA diversity (HLA-A, -B, and -DRB1 loci) of an Austroasiatic Munda population from Northeast India and its relationships with other populations from India and Southeast Asia. Because… 
The genetic legacy of continental scale admixture in Indian Austroasiatic speakers
TLDR
Using genome-wide genotype data of 102 Munda speakers and contextual data from South and Southeast Asia, admixture dates between 2000–3800 years ago for different populations of Munda are retrieved and the grouping of the MundA speakers into North and South Munda based on linguistics is in concordance with genome- wide data.
HLA‐A*02 repertoires in three defined population groups from North and Central India: Punjabi Khatries, Kashmiri Brahmins and Sahariya Tribe
TLDR
The HLA‐A*02 repertoire was investigated in North Indian caste populations using Luminex‐based high‐resolution rSSO method and a striking observation was the high occurrence of A*02:11 at the repertoire level, which may be representation of ancient Austro‐Asiatic genetic pool.
The Cradle of the Munda: Birth of a New Branch of Austroasiatic
The location of the origin of the Munda speaking peoples of India has been a contested subject since the time of Sarat Chandra Roy (1912), the doyen of Indian ethnology. The recent genetic studies
Reconstructing Austroasiatic prehistory
The issue of the homeland, dating and expansion of the Austroasiatic languages and its correlation with results from other disciplines, particularly archaeology and genetics, remains contentious.
A Genetic Focus on the Peopling History of East Asia: Critical Views
TLDR
This paper reviews the current genetic evidence related to the peopling history of East Asia with a critical view on some interpretations and hopes to provide a useful reference for further interdisciplinary studies on the authors' past.
HLA DNA Sequence Variation among Human Populations: Molecular Signatures of Demographic and Selective Events
TLDR
HLA DNA sequences advantageously complement HLA allele frequencies as a source of data used to explore the genetic history of human populations, and that their analysis allows a more thorough investigation of human MHC molecular evolution.
Allele Frequency Estimation from Ambiguous Data: Using Resampling Schema in Validating Frequency Estimates and in Selective Neutrality Testing
TLDR
Overall, it is shown that using a resampling scheme in validating frequency estimates is effective when alternative frequency estimates are available and appears to be the unique way to test selective neutrality when only frequency data are available to describe the genetic structure of populations.
Distinct evolutionary strategies of human leucocyte antigen loci in pathogen-rich environments
TLDR
The inverse relationship between genetic diversity and pathogen richness at different loci indicates that HLA genes have adopted distinct evolutionary strategies to provide immune protection in pathogen-rich environments.
Malay minorities in The Tenasserim coast
This paper discusses the Malay Minorities of the Malay Minorities in the Tenasserim Coast. And Tanintharyi Division is an administrative region of Myanmar at present. When we look closely at some of
Binding affinities of 438 HLA proteins to complete proteomes of seven pandemic viruses and distributions of strongest and weakest HLA peptide binders in populations worldwide
TLDR
Detailed peptide‐binding affinities between 438 HLA Class I and Class II proteins and complete proteomes of seven pandemic human viruses are reported and possible signatures of natural selection on HLA promiscuous alleles due to past pathogenic infections are discussed.
...
...

References

SHOWING 1-10 OF 136 REFERENCES
Y-chromosome evidence suggests a common paternal heritage of Austro-Asiatic populations
TLDR
The findings are consistent with the linguistic evidence, which suggests that the linguistic ancestors of the Austro-Asiatic populations have originated in India and then migrated to Southeast Asia.
Population genetic structure in Indian Austroasiatic speakers: the role of landscape barriers and sex-specific admixture.
TLDR
It is proposed that AA speakers in India today are derived from dispersal from southeast Asia, followed by extensive sex-specific admixture with local Indian populations, strongly supporting the first of the two hypotheses.
Phylogeography of mtDNA haplogroup R7 in the Indian peninsula
TLDR
Among Indo-Europeans, and particularly in Dravidians, the haplogroup is, despite its lower frequency, phylogenetically more divergent, while among the Munda speakers only one sub-clade of R7, i.e. R7a1, can be observed.
Challenging views on the peopling history of East Asia: the story according to HLA markers.
TLDR
A new overlapping model where northward and southward opposite migrations occurring at different periods overlapped is suggested, as genetic contribution of ancient human migrations through a northern route has probably been quite substantial.
Genomic structures and population histories of linguistically distinct tribal groups of India
TLDR
Evidence is provided in support of the hypothesis that the Austro-Asiatic speakers are the most ancient inhabitants of India and the earlier finding that some of the western Eurasian haplogroups found in India may have been present in India prior to the entry of Aryan speakers.
Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations
TLDR
Austronesian populations of the Pacific and Austro-Asiatic populations of southeast Asia most frequently carry the 9-bp deletion in that region implying their shared common ancestry in haplogroup B, and the low polymorphism in the D-loop sequence of the Nicobarese B5a samples suggests their recent origin and a founder effect, probably involving migration from southeast Asia.
Comparing linguistic and genetic relationships among east asian populations: a study of the Rh and GM polymorphisms
TLDR
Several polymorphic systems must be analysed to draw more conclusive inferences about the genetic history of populations in East Asia, as attested by the numerous studies on variation of molecular markers in these populations published during the last four or five years.
Genetic affinities of north and northeastern populations of India: inference from HLA-based study.
TLDR
The presence of Caucasoid element in north Indian population was observed, however, differential admixturing among Sunnis and Shias with the other north Indians was evident and Northeastern populations showed genetic affinity with Mongoloids from southeast Asia.
Origins of the Austro‐Asiatic Populations
TLDR
A common paternal origin of Austro-Asiatics and the migration of paternal ancestors of Austo-Asiatic populations from East to South Asia, followed by the origin ofAustro- asiatic languages which subsequently spread to Southeast Asia, with primarily male-mediated migrations is inferred.
Molecular Genetic Study on the Status of Transitional Groups of Central India: Cultural Diffusion or Demic Diffusion?
Abstract Two different models of diffusion - demic and cultural - have been proposed as an explanation for the spread of languages. Recent studies have shown that in some cases the dispersal of the
...
...