The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.

@article{Wilkinson1996TheAT,
  title={The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.},
  author={Marc G. Wilkinson and Martin Samuels and Taito Takeda and William Toone and J C Shieh and Takashi Toda and Jonathan B. A. Millar and Nic Jones},
  journal={Genes & development},
  year={1996},
  volume={10 18},
  pages={2289-301}
}
The atf1+ gene of Schizosaccharomyces pombe encodes a bZIP transcription factor with strong homology to the mammalian factor ATF-2. ATF-2 is regulated through phosphorylation in mammalian cells by the stress-activated mitogen-activated protein (MAP) kinases SAPK/JNK and p38. We show here that the fission yeast Atf1 factor is also regulated by a stress-activated kinase, Sty1. The Sty1 kinase is stimulated by a variety of different stress conditions including osmotic and oxidative stress and heat… CONTINUE READING
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