The Association of Migraine with Ischemic Stroke

  title={The Association of Migraine with Ischemic Stroke},
  author={Tobias Kurth},
  journal={Current Neurology and Neuroscience Reports},
  • T. Kurth
  • Published 27 February 2010
  • Psychology, Medicine
  • Current Neurology and Neuroscience Reports
Migraine is a common, chronic–intermittent primary headache disorder affecting mostly women. The migraine pathophysiology involves both the neuronal and vascular systems, and in some patients, transient neurologic symptoms occur, which are known as migraine aura. A large body of literature supports an association between migraine and ischemic stroke, which is apparent mostly in young women with migraine with aura. Further increased risks have been observed particularly in smokers and women who… 

Migraine as a risk factor for young patients with ischemic stroke: a case–control study

Migraine with aura was found to be more common in ischemic stroke in young patients and was an independent risk factor in women, and separate analysis for gender demonstrated that it was only a risk factor for women but not for men.

Aspects of migraine and patent foramen ovale in ischemic stroke

Most stroke patients had a favorable outcome after stroke and there was no difference in stroke severity depending on migraine status, and migraine was associated with PFO.

Ischemic stroke subtypes and migraine with visual aura in the ARIC study

In participants with migraine with visual aura in late middle age, increased risk of cardioembolic stroke was observed, over the period of 20 years, which is specific to older migraineurs.


Migraine may bring a suffering phase in an individual's schedule yet it can be handled with the familiarity of some self-care remedies and by making simple modifications in the routine lifestyle, which may facilitate to pave the clear way to recovery and make things easier for migraine management.

Migraine: risk factor and comorbidity

The burden of migraine strongly increases considering its linkage with other psychiatric, neurological, cardiovascular and cerebrovascular diseases, and highlighting these relationships is important to improve treatment strategies, broaden the knowledge of the pathophysiology and understand if migraine is per se a modifiable risk factor for some disorders.

The association of migraine with menstrually related mood disorders and childhood sexual abuse.

Women with MRMD may be vulnerable to the development of MA, and a history of CSA in women with a MRMD appears to increase that vulnerability, and MRMDs and MA should be included among other poor mental and physical health outcomes of an abuse history.

Migraine prevalence in patients with unruptured intracranial aneurysms: A case–control study

A case–control study is performed to compare lifetime migraine prevalence in patients with UIA, patients with a history of transient ischemic attact (TIA) or isChemic stroke and controls without a historyof aSAH, TIA orIschemic stroke.

Cerebellar and Cerebral Autoregulation in Migraine

This first-time analysis of Cerebellar autoregulation in migraine did not show a specific cerebellar dysautoregulations in the interictal period, however, more static autoreGulatory properties are impaired in persons with migraine with aura both in the cerebellary and anterior circulation.



Relation between migraine and stroke

Migraine and risk of cardiovascular disease in women.

In this large, prospective cohort of women, active migraine with aura was associated with increased risk of major CVD, myocardial infarction, ischemic stroke, and death due to isChemic CVD as well as with coronary revascularization and angina.

Headache, cerebrovascular symptoms, and stroke

Migraines and other headaches, particularly those accompanied by aura, were associated with an increased occurrence of stroke/TIA symptoms and ischemic stroke events.

The epidemiology of migraine.

Migraine and risk of cardiovascular disease in men.

In this large prospective cohort of apparently healthy men, migraine was associated with increased risk of major CVD, which was driven by increase risk of myocardial infarction.

Duration, frequency, recency, and type of migraine and the risk of ischaemic stroke in women of childbearing age

The data support earlier reports of a relation between ischaemic stroke and migraine with aura, and the risk seems particularly high in those whose initial migraine type involved aura occurring more than 12 times per year.

Migraine headache in middle age and late-life brain infarcts.

Migraine with aura in midlife was associated with late-life prevalence of cerebellar infarct-like lesions on MRI, consistent with the hypothesis that migraine with auraIn midlife is associated withLate-life vascular disease in the cerebellum and in women.

Cardiovascular risk factors and migraine

The odds of having an elevated Framingham risk score for CHD were approximately doubled for the migraineurs with aura, and individuals without migraine have a higher cardiovascular risk profile thanindividuals without migraine.

History of Migraine and the Risk of Spontaneous Cervical Artery Dissection

Findings are consistent with the hypothesis that migraine may represent a predisposing condition for sCAD, and when the frequencies of family history of migraine were compared.

Magnetic Resonance Imaging in Migraine and Tension‐Type Headache

The findings indicate that both migraine and tension‐type headache may be associated with early pathologic changes in the brain and may share, at least in part, common pathogenic pathways.