The Association of Early and Recent Psychosocial Life Stress With Leukocyte Telomere Length

@article{Verhoeven2015TheAO,
  title={The Association of Early and Recent Psychosocial Life Stress With Leukocyte Telomere Length},
  author={Josine E. Verhoeven and Patricia van Oppen and Eli Puterman and Bernet M. Elzinga and Brenda W.J.H. Penninx},
  journal={Psychosomatic Medicine},
  year={2015},
  volume={77},
  pages={882–891}
}
Objectives Chronic exposure to psychosocial stressors is related to worse somatic health. This association applies both to stressors early in life, such as childhood adversities, and more recent life stress, such as stressful life events. This study examined whether accelerated telomere shortening, as an indicator of cellular aging, might be an explanatory mechanism. Methods We examined whether childhood adversities and recent stressful life events were associated with shorter telomeres in 2936… 

Early and recent psychosocial stress and telomere length in older adults

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Results imply that interventions should focus on establishing strong social connections, psychological resources, and health-maintaining behaviors when attempting to ameliorate stress-related decline in telomere length among at-risk individuals.

The association of individual changes in stressful life events and telomere length over time in twins aged 50 years and above.

The findings in an older population show a causal relation between increase in life stress on accelerated LTL shortening by using intra-individual time-varying analysis.

Cold parenting is associated with cellular aging in offspring: A retrospective study

Transcriptomic analyses and leukocyte telomere length measurement in subjects exposed to severe recent stressful life events

Data suggest an association between exposures to recent stressful life events in adulthood and alterations in the immune, inflammatory and oxidative stress pathways, which could be also involved in the negative effect of Stressful life events on leukocyte telomere length.
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