The Association of Bone Marrow Lesions with Pain in Knee Osteoarthritis

@article{Felson2001TheAO,
  title={The Association of Bone Marrow Lesions with Pain in Knee Osteoarthritis},
  author={D. Felson and C. Chaisson and C. Hill and S. Totterman and M. Gale and K. Skinner and L. Kazis and D. Gale},
  journal={Annals of Internal Medicine},
  year={2001},
  volume={134},
  pages={541-549}
}
Knee osteoarthritis affects 11% to 15% of the U.S. population 65 years of age or older (1) and is a leading cause of disability in the elderly. The major source of disability and care seeking for patients with osteoarthritis is pain in the knee (2). The cause of knee pain in patients with osteoarthritis is unclear. Osteoarthritis has been considered a disease whose characteristic pathologic feature is loss of hyaline articular cartilage, but that tissue contains no pain fibers. Pain fibers are… Expand
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