The Association between C9orf72 Repeats and Risk of Alzheimer's Disease and Amyotrophic Lateral Sclerosis: A Meta-Analysis

@inproceedings{Shu2016TheAB,
  title={The Association between C9orf72 Repeats and Risk of Alzheimer's Disease and Amyotrophic Lateral Sclerosis: A Meta-Analysis},
  author={Li Yu Shu and Qiying Sun and Yuan Zhang and Qian Xu and Jifeng Guo and Xinxiang Yan and Beisha Tang},
  booktitle={Parkinson's disease},
  year={2016}
}
C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in Caucasian populations. However, the relationship between C9orf72 repeats and Alzheimer's disease (AD) was not clear. Additionally, there were few articles assessing C9orf72 in other ethnicities with ALS. In this meta-analysis, we aimed to investigate the relationship between C9orf72 repeat expansions (≥30 repeats) and intermediate repeat copies (20-29 repeats) and AD or ALS. The… CONTINUE READING
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