The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence.

@article{Bom2015TheAF,
  title={The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence.},
  author={Vin{\'i}cius Leite Pedro Bom and Patr{\'i}cia Alves de Castro and Lizziane Kretli Winkelstr{\"o}ter and Marçal Marin{\'e} and Juliana Issa Hori and Leandra N{\'a}ira Zambelli Ramalho and Thaila Fernanda Dos Reis and Maria Helena S. Goldman and Neil Andrew Brown and Ranjith Kumar Rajendran and Gordon Ramage and Louise A Walker and Carol A Munro and Marina Campos Rocha and Iran Malavazi and Daisuke Hagiwara and Gustavo Henrique Goldman},
  journal={Eukaryotic cell},
  year={2015},
  volume={14 8},
  pages={
          728-44
        }
}
Aspergillus fumigatus is an opportunistic pathogenic fungus able to infect immunocompromised patients, eventually causing disseminated infections that are difficult to control and lead to high mortality rates. It is important to understand how the signaling pathways that regulate these factors involved in virulence are orchestrated. Protein phosphatases are central to numerous signal transduction pathways. Here, we characterize the A. fumigatus protein phosphatase 2A SitA, the Saccharomyces… CONTINUE READING
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