The Arrest of Biological Time as a Bridge to Engineered Negligible Senescence

@article{Lemler2004TheAO,
  title={The Arrest of Biological Time as a Bridge to Engineered Negligible Senescence},
  author={Jerry Lemler and S. Harris and Charles Platt and Todd M Huffman},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1019}
}
Abstract: Biological systems can remain unchanged for several hundred years at cryogenic temperatures. In several hundred years, current rapid scientific and technical progress should lead to the ability to reverse any biological damage whose reversal is not forbidden by physical law. We therefore explore whether contemporary people facing terminal conditions might be preserved well enough today for their eventual recovery to be compatible with physical law. The ultrastructure of the brain can… Expand

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References

SHOWING 1-7 OF 7 REFERENCES
Freezing of living cells: mechanisms and implications.
  • P. Mazur
  • Chemistry, Medicine
  • The American journal of physiology
  • 1984
TLDR
A new view of the mechanism of slow freezing injury ought to facilitate the development of procedures for the preservation of complex assemblages of cells of biological, medical, and agricultural significance. Expand
The technical feasibility of cryonics.
TLDR
The limits of what medical technology should eventually be able to achieve and whether the repair of frozen tissue is within those limits are considered. Expand
Recovery of integrative central nervous function after one hour global cerebro-circulatory arrest in normothermic cat
TLDR
Observations demonstrate that despite these lesions the central nervous system is able to recover integrative neurological function after cerebro-circulatory arrest in normothermia of as long as 1 h. Expand
Vitrification as an approach to cryopreservation.
TLDR
Some of the principles of vitrification are reviewed, the current state of the art is described, how a practical vitrification scheme might work, and how the principles relate to and illuminate the principles and practices of freezing are noted. Expand
Nanosystems - molecular machinery, manufacturing, and computation
TLDR
This book discusses molecular manufacturing systems, nanoscale Structural Components, and Nanomechanical Computational Systems, as well as some of the techniques used in macromolecular engineering and its applications. Expand
On Immortality: An Interim Solution
The Prospect of Immortality