The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments

@article{Amann2001TheAC,
  title={The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments},
  author={Kurt J. Amann and Thomas D. Pollard},
  journal={Nature Cell Biology},
  year={2001},
  volume={3},
  pages={306-310}
}
Regulated assembly of actin-filament networks provides the mechanical force that pushes forward the leading edge of motile eukaryotic cells and intracellular pathogenic bacteria and viruses. When activated by binding to actin filaments and to the WA domain of Wiskott–Aldrich-syndrome protein (WASP)/Scar proteins, the Arp2/3 complex nucleates new filaments… CONTINUE READING