The Arabidopsis phenylalanine insensitive growth mutant exhibits a deregulated amino acid metabolism.

@article{Voll2004TheAP,
  title={The Arabidopsis phenylalanine insensitive growth mutant exhibits a deregulated amino acid metabolism.},
  author={Lars Matthias Voll and Erin E Allaire and Gabriele Fiene and Andreas P M Weber},
  journal={Plant physiology},
  year={2004},
  volume={136 2},
  pages={3058-69}
}
Amino acids and amino acid analogs have been used in numerous genetic screens to isolate mutants deficient in amino acid biosynthetic pathways or in the regulation of amino acid metabolism. Several of these mutants exhibit relaxed feedback control of branched amino acid biosynthetic pathways and are thus resistant to accumulation of pathway end products. For example, feedback-regulated enzymes of the shikimate pathway are anthranilate synthase on the branch leading to Trp and chorismate mutase… CONTINUE READING
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