The Application of Malononitriles as Microviscosity Probes in Pharmaceutical Systems

@article{Laporte1995TheAO,
  title={The Application of Malononitriles as Microviscosity Probes in Pharmaceutical Systems},
  author={Sherry L Laporte and Abizer I Harianawala and Robin H. Bogner},
  journal={Pharmaceutical Research},
  year={1995},
  volume={12},
  pages={380-386}
}
Three molecules were investigated for their ability to distinguish variations in the microviscosity of the surrounding medium. Julolidinemalononitrile (JMN), p-(N-dimethylaminobenzylidene) malononitrile (BMN), and p-(N-dimethylaminocinnamylidene) malononitrile (CMN) were dissolved in media of various micro- and bulk viscosities. The fluorescence intensity… CONTINUE READING