The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells

Abstract

Jesridonin, a small molecule obtained through the structural modification of Oridonin, has extensive antitumor activity. In this study, we evaluated both its in vitro activity in the cancer cell line EC109 and its in vivo effect on tumor xenografts in nude mice. Apoptosis induced by Jesridonin was determined using an MTT assay, Annexin-V FITC assay and… (More)
DOI: 10.1371/journal.pone.0130284

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