The Antiprogestin Steroid RU 486 and Human Fertility Control

@inproceedings{Baulieu1985TheAS,
  title={The Antiprogestin Steroid RU 486 and Human Fertility Control},
  author={Etienne Emile Baulieu},
  booktitle={Reproductive Biology},
  year={1985}
}
Etienne-Emile Baulieu Universite de Paris Sud Lab Hormone INSERM U33 94270 Bicetre, France We summarize the basic principles and the main experimental data that have led to the clinical use of RU 486's antiprogestin activity in human fertility control ("contragestion"). The structural features of the receptor binding properties of this steroidal antihormone are reported, as well as experiments at molecular, cellular and physiological levels in rodents and primates. RU 486 (17B-hydroxy-llB-(4… CONTINUE READING

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