The Antifungal Activity of Sarcococca saligna Ethanol Extract and its Combination Effect with Fluconazole against Different Resistant Aspergillus Species

  title={The Antifungal Activity of Sarcococca saligna Ethanol Extract and its Combination Effect with Fluconazole against Different Resistant Aspergillus Species},
  author={Kamyar Mollazadeh Moghaddam and Mohammad Arfan and Jamal Rafique and S. Rezaee and Parisa Jafari Fesharaki and Ahmad Reza Gohari and Ahmad Reza Shahverdi},
  journal={Applied Biochemistry and Biotechnology},
Microbial resistance is a major drawback in chemotherapy of microbial or fungal infection disease. In this study, the antifungal activity of ethanol extract of a selected plant (Sarcococca saligna) has been investigated against clinical isolates of Aspergillus niger, Aspergillus treus, Aspergillus flavus, and Aspergillus fumigatus. Also, the enhancement of the antifungal activity of fluconazole by this extract was further evaluated against mentioned test strains. Conventional disk diffusion… 
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