The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

@inproceedings{Carter2011TheAF,
  title={The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile},
  author={Glen P. Carter and Gillian R Douce and Revathi Govind and Pauline M. Howarth and Kate E. Mackin and Janice Spencer and Anthony M. Buckley and Ana Antunes and Despina Kotsanas and Grant A. Jenkin and Bruno Dupuy and Julian I Rood and Dena Lyras},
  booktitle={PLoS pathogens},
  year={2011}
}
Nosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial pathogens that are well adapted to surviving and proliferating in this setting, after which they can infect susceptible patients. This is clearly the case for bacterial pathogens such as Methicillin Resistant Staphylococcus aureus (MRSA) and Vancomycin Resistant Enterococcus (VRE… CONTINUE READING
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