The Anolis Lizard Genome: An Amniote Genome without Isochores

  title={The Anolis Lizard Genome: An Amniote Genome without Isochores},
  author={Matthew K. Fujita and Scott V Edwards and Chris P. Ponting},
  booktitle={Genome biology and evolution},
Isochores are large regions of relatively homogeneous nucleotide composition and are present in the genomes of all mammals and birds that have been sequenced to date. The newly sequenced genome of Anolis carolinensis provides the first opportunity to quantify isochore structure in a nonavian reptile. We find Anolis to have the most compositionally homogeneous genome of all amniotes sequenced thus far, a homogeneity exceeding that for the frog Xenopus. Based on a Bayesian algorithm, Anolis has… CONTINUE READING
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