The Androgen Insensitivity Syndrome (Testicular Feminization): A Clinicopathologic Study of 43 Cases

  title={The Androgen Insensitivity Syndrome (Testicular Feminization): A Clinicopathologic Study of 43 Cases},
  author={Joanne K.L. Rutgers and Robert E. Scully},
  journal={International Journal of Gynecological Pathology},
  • J. Rutgers, R. Scully
  • Published 1 April 1991
  • Medicine
  • International Journal of Gynecological Pathology
Summary:Forty-three patients with the androgen insensitivity syndrome (AIS), ages 14 to 83 (average 27) years, were studied. Forty patients had complete AIS and three patients had incomplete AIS. Microscopic examination of the testes revealed immature tubules, which contained rare spermatogonia in 28% of the cases. Prominent Leydig cells and a spindle-cell stroma resembling ovarian stroma were found in a majority of cases. The organization of the testicular parenchyma could be classified into… 

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