The Analytic Distribution of Fractional Anisotropy in Diffusion Mri

INTRODUCTION: Fractional anisotropy (FA) is a popular scalar measure of voxelwise diffusion characteristics, computed by a nonlinear transformation of the tensor eigenvalues [1]. Despite its ubiquitous use in diffusion MRI studies, the statistical distribution of FA has remained unknown; statistical inference on FA images has either involved a Gaussianity… CONTINUE READING