The Amygdala Is Enlarged in Children But Not Adolescents with Autism; the Hippocampus Is Enlarged at All Ages

@article{Schumann2004TheAI,
  title={The Amygdala Is Enlarged in Children But Not Adolescents with Autism; the Hippocampus Is Enlarged at All Ages},
  author={C. Schumann and J. Hamstra and B. Goodlin-Jones and L. Lotspeich and H. Kwon and M. Buonocore and C. R. Lammers and A. Reiss and D. Amaral},
  journal={The Journal of Neuroscience},
  year={2004},
  volume={24},
  pages={6392 - 6401}
}
  • C. Schumann, J. Hamstra, +6 authors D. Amaral
  • Published 2004
  • Psychology, Medicine
  • The Journal of Neuroscience
  • Autism is a neurodevelopmental disorder characterized by impairments in reciprocal social interaction, deficits in verbal and nonverbal communication, and a restricted repertoire of activities or interests. We performed a magnetic resonance imaging study to better define the neuropathology of autistic spectrum disorders. Here we report findings on the amygdala and the hippocampal formation. Borders of the amygdala, hippocampus, and cerebrum were defined, and their volumes were measured in male… CONTINUE READING
    702 Citations
    Amygdala Enlargement in Toddlers with Autism Related to Severity of Social and Communication Impairments
    • 241
    Amygdalar volume and behavioral development in autism.
    • 164
    • PDF
    A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism
    • 62
    Increased rate of amygdala growth in children aged 2 to 4 years with autism spectrum disorders: a longitudinal study.
    • 138
    • PDF
    Anatomy and aging of the amygdala and hippocampus in autism spectrum disorder: an in vivo magnetic resonance imaging study of Asperger syndrome
    • C. Murphy, Q. Deeley, +15 authors D. Murphy
    • Psychology, Medicine
    • Autism research : official journal of the International Society for Autism Research
    • 2012
    • 36
    • Highly Influenced
    Laterobasal amygdalar enlargement in 6- to 7-year-old children with autism spectrum disorder.
    • 69
    • PDF
    Longitudinal study of amygdala volume and joint attention in 2- to 4-year-old children with autism.
    • 200
    • Highly Influenced
    • PDF
    Amygdala and hippocampus enlargement during adolescence in autism.
    • 83
    Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism
    • 91
    • PDF

    References

    SHOWING 1-10 OF 68 REFERENCES
    MRI volumes of amygdala and hippocampus in non–mentally retarded autistic adolescents and adults
    • 450
    • Highly Influential
    Brain structural abnormalities in young children with autism spectrum disorder
    • 805
    A pilot study of amygdala volumes in pediatric generalized anxiety disorder
    • 283
    • PDF
    Outcome in High-Functioning Adults with Autism with and Without Early Language Delays: Implications for the Differentiation Between Autism and Asperger Syndrome
    • P. Howlin
    • Psychology, Medicine
    • Journal of autism and developmental disorders
    • 2003
    • 541
    Neuroanatomic observations of the brain in autism: a review and future directions
    • 810
    Neuropsychological correlates of early symptoms of autism.
    • 284
    Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging.
    • 387
    • Highly Influential
    Investigation of neuroanatomical differences between autism and Asperger syndrome.
    • 143
    • PDF
    The amygdala theory of autism
    • 999
    • PDF