The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.

@article{Ernkvist2009TheAS,
  title={The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.},
  author={Mira Ernkvist and Nathalie Luna Persson and St{\'e}phane Audebert and Patrick L{\'e}cine and Indranil Sinha and Miaoliang Liu and Marc Alexander Schl{\"u}ter and Arie Horowitz and Karin Aase and Thomas N. Weide and Jean-Paul Borg and Arindam Majumdar and Lars Holmgren},
  journal={Blood},
  year={2009},
  volume={113 1},
  pages={244-53}
}
Controlled regulation of Rho GTPase activity is an essential component mediating growth factor-stimulated migration. We have previously shown that angiomotin (Amot), a membrane-associated scaffold protein, plays a critical role during vascular patterning and endothelial migration during embryogenesis. However, the signaling pathways by which Amot controls directional migration are not known. Here we have used peptide pull-down and yeast 2-hybrid (Y2H) screening to identify proteins that… CONTINUE READING
56 Extracted Citations
34 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 56 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 34 references

Mass Spectrometry Protein Sequence DataBase (MSDB)

  • Imperial College London
  • http://cscfserve.hh.med.ic.ac.uk/msdb.html…
  • 2007

Similar Papers

Loading similar papers…