The American Journal of Physiology


The isolated dog heart has been shown to function without significant impairment when perfused with physiological solutions of varied pH values between 7.0 and 7.8 (1). Recently it was demonstrated that the dog heart in situ may function without serious impairment until a blood pH value of 6.25 is attained by infusion of hydrochloric or lactic acid into the… (More)


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