The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures.

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@article{Shioi1995TheAA, title={The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures.}, author={Junichi Shioi and Menelas N. Pangalos and James A. Ripellino and Dido Vassilacopoulou and Catherine Mytilineou and Richard U. Margolis and Nikolaos K. Robakis}, journal={The Journal of biological chemistry}, year={1995}, volume={270 20}, pages={11839-44} }