The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor

@article{Zhang2013TheAO,
  title={The Alteration of MiR-222 and Its Target Genes in Nickel-Induced Tumor},
  author={Jing Zhang and Yang Zhou and Lin Ma and Shunquan Huang and Ruijin Wang and Rongrong Gao and Youjun Wu and Hongjun Shi and Jun Zhang},
  journal={Biological Trace Element Research},
  year={2013},
  volume={152},
  pages={267-274}
}
Nickel is an important kind of metal and a necessary trace element in people’s production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncogenes and inactivation of anti-oncogenes caused by gene point mutation, gene deletion, gene amplification, DNA methylation, chromosome condensation, and so on that were induced by… CONTINUE READING
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