The Aldehyde Oxidase Gene Cluster in Mice and Rats

@article{Kurosaki2004TheAO,
  title={The Aldehyde Oxidase Gene Cluster in Mice and Rats},
  author={M. Kurosaki and M. Terao and M. M. Barzago and A. Bastone and Davide Bernardinello and M. Salmona and E. Garattini},
  journal={Journal of Biological Chemistry},
  year={2004},
  volume={279},
  pages={50482 - 50498}
}
Mammalian molybdo-flavoenzymes are oxidases requiring FAD and molybdopterin (molybdenum cofactor) for their catalytic activity. This family of proteins was thought to consist of four members, xanthine oxidoreductase, aldehyde oxidase 1 (AOX1), and the aldehyde oxidase homologues 1 and 2 (AOH1 and AOH2, respectively). Whereas the first two enzymes are present in humans and various other mammalian species, the last two proteins have been described only in mice. Here, we report on the… Expand
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