The Administration of rt-PA (Activase®) for the Treatment of Empyema in an Adult Patient

@article{Emerson2009TheAO,
  title={The Administration of rt-PA (Activase®) for the Treatment of Empyema in an Adult Patient},
  author={Christopher R. Emerson and Christine M. Bercume and Marilena S. Antonopoulos and Nino Marzella},
  journal={Journal of Pharmacy Practice},
  year={2009},
  volume={22},
  pages={117 - 123}
}
The administration of various fibrinolytic agents for the treatment of empyema has been reported in past studies. Most of the current literature has shown favorable outcomes in terms of increased tube drainage, improved chest radiography, and reduction in surgical intervention. However, a randomized controlled trial that compared streptokinase to placebo showed no significant reduction in mortality. To date, there have been no randomized controlled trials evaluating the safety, efficacy, and… Expand
1 Citations
Intrapleural Tissue Plasminogen Activator for the Treatment of Parapneumonic Effusion
  • 15

References

SHOWING 1-10 OF 20 REFERENCES
Tissue Plasminogen Activator as an Adjuvant Therapy for Pleural Empyema in Pediatric Patients
  • 24
  • Highly Influential
Effectiveness and safety of tissue plasminogen activator in the management of complicated parapneumonic effusions.
  • 53
  • Highly Influential
  • PDF
U.K. Controlled trial of intrapleural streptokinase for pleural infection.
  • 629
  • PDF
Use of fibrinolytic agents in the management of complicated parapneumonic effusions and empyemas
  • 89
  • PDF
Intrapleural fibrinolysis for parapneumonic effusion and empyema in children.
  • 88
  • Highly Influential
Intrapleural streptokinase for empyema and complicated parapneumonic effusions.
  • 187
Medical and surgical treatment of parapneumonic effusions : an evidence-based guideline.
  • 574
...
1
2
...