The Activity of Peptides of the Calcitonin Family in Bone.

@article{Naot2019TheAO,
  title={The Activity of Peptides of the Calcitonin Family in Bone.},
  author={Dorit Naot and David S. Musson and Jillian Cornish},
  journal={Physiological reviews},
  year={2019},
  volume={99 1},
  pages={
          781-805
        }
}
Calcitonin was discovered over 50 yr ago as a new hormone that rapidly lowers circulating calcium levels. This effect is caused by the inhibition of calcium efflux from bone, as calcitonin is a potent inhibitor of bone resorption. Calcitonin has been in clinical use for conditions of accelerated bone turnover, including Paget's disease and osteoporosis; although in recent years, with the development of drugs that are more potent inhibitors of bone resorption, its use has declined. A number of… 
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TLDR
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TLDR
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