The ATP-dependent lon protease of Salmonella enterica serovar Typhimurium regulates invasion and expression of genes carried on Salmonella pathogenicity island 1.

@article{Takaya2002TheAL,
  title={The ATP-dependent lon protease of Salmonella enterica serovar Typhimurium regulates invasion and expression of genes carried on Salmonella pathogenicity island 1.},
  author={Akiko Takaya and Toshifumi Tomoyasu and Akane Tokumitsu and Mizue Morioka and Tomoko Yamamoto},
  journal={Journal of bacteriology},
  year={2002},
  volume={184 1},
  pages={
          224-32
        }
}
An early step in the pathogenesis of Salmonella enterica serovar Typhimurium infection is bacterial penetration of the intestinal epithelium. Penetration requires the expression of invasion genes found in Salmonella pathogenicity island 1 (SPI1). These genes are controlled in a complex manner by regulators in SPI1, including HilA and InvF, and those outside SPI1, such as two-component regulatory systems and small DNA-binding proteins. We report here that the expression of invasion genes and the… CONTINUE READING

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