The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways.

@article{Whiteway1985TheAG,
  title={The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways.},
  author={Malcolm Whiteway and Jack W Szostak},
  journal={Cell},
  year={1985},
  volume={43 2 Pt 1},
  pages={483-92}
}
Mutations in the yeast gene ARD1 lead to inability to respond to alpha-factor, inability to enter stationary phase, and inability to sporulate, suggesting an important role for the ARD1 gene product in controlling the switch between the mitotic cell cycle and alternative cell fates. MATa, ard1 cells seem to be defective in the expression of all a-specific functions, whereas MAT alpha, ard1 cells respond normally to a-factor. We propose that ARD1 is required for the expression of genes involved… CONTINUE READING
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