The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana.

@article{Doelling2002TheAE,
  title={The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana.},
  author={Jed H. Doelling and Joseph M. Walker and Eric M Friedman and Allison R Thompson and Richard D Vierstra},
  journal={The Journal of biological chemistry},
  year={2002},
  volume={277 36},
  pages={33105-14}
}
The vacuole/lysosome serves an important recycling function during starvation and senescence in eukaryotes via a process called autophagy. Here bulk cytosolic constituents and organelles become sequestered in specialized autophagic vesicles, which then deliver their cargo to the vacuole for degradation. In yeasts, genetic screens have identified two novel post-translational modification pathways remarkably similar to ubiquitination that are required for autophagy. From searches of the… CONTINUE READING
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