The ADAM33 S2 polymorphism is associated with susceptibility to pediatric asthma in the Chinese Han population.

@article{Fan2015TheAS,
  title={The ADAM33 S2 polymorphism is associated with susceptibility to pediatric asthma in the Chinese Han population.},
  author={Jin-gang Fan and Zhao-An Wang and Hong-xiang Zhao},
  journal={Genetic testing and molecular biomarkers},
  year={2015},
  volume={19 10},
  pages={573-8}
}
BACKGROUND The disintegrin and metalloprotease domain containing protein 33 (ADAM33) is a novel susceptibility gene for asthma and airway hyperresponsiveness, particularly in the Asian population. We investigated the influence of ADAM33 polymorphisms on the serum levels of ADAM33 and the susceptibility to pediatric asthma in the Chinese Han population. METHODS Polymerase chain reaction-restriction fragment length polymorphism analysis was employed to study the genotypic distribution of F+1… CONTINUE READING
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