The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

@article{Eberharter1999TheAC,
  title={The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.},
  author={Anton Eberharter and David E. Sterner and David M. Schieltz and Ali Mohammed Ali Hassan and John R. Yates and Shelley L Berger and Jerry L. Workman},
  journal={Molecular and cellular biology},
  year={1999},
  volume={19 10},
  pages={6621-31}
}
We have identified two Gcn5-dependent histone acetyltransferase (HAT) complexes from Saccharomyces cerevisiae, the 0.8-MDa ADA complex and the 1.8-MDa SAGA complex. The SAGA (Spt-Ada-Gcn5-acetyltransferase) complex contains several subunits which also function as part of other protein complexes, including a subset of TATA box binding protein-associated factors (TAFIIs) and Tra1. These observations raise the question of whether the 0.8-MDa ADA complex is a subcomplex of SAGA or whether it is a… CONTINUE READING
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