The AC4 Protein of a Cassava Geminivirus Is Required for Virus Infection.

  title={The AC4 Protein of a Cassava Geminivirus Is Required for Virus Infection.},
  author={Kegui Chen and Behnam Khatabi and Vincent N. Fondong},
  journal={Molecular plant-microbe interactions : MPMI},
Geminiviruses (family Geminiviridae) are among the most devastating plant viruses worldwide, causing severe damage in crops of economic and subsistence importance. These viruses have very compact genomes and many of the encoded proteins are multifunctional. Here, we investigated the role of the East African cassava mosaic Cameroon virus (EACMCV) AC4 on virus infectivity in Nicotiana benthamiana. Results showed that plants inoculated with EACMCV containing a knockout mutation in an AC4 open… 
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Analysis of Pathogenicity and Virulence Factors of Ageratum leaf curl Sichuan virus
Ageratum leaf curl Sichuan virus (ALCScV) is a novel monopartite begomovirus, which was identified from Ageratum conyzoides plants in Sichuan Province, China. In this study, we showed that ALCScV can
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Tomato auxin biosynthesis/signaling is reprogrammed by the geminivirus to enhance its pathogenicity.
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C4, the Pathogenic Determinant of Tomato Leaf Curl Guangdong Virus, May Suppress Post-transcriptional Gene Silencing by Interacting With BAM1 Protein
C4 is a pathogenic determinant of ToLCGdV, and C4 may suppress post-transcriptional gene silencing (PTGS) by interacting with BAM1 in the cell-to-cell spread of RNAi.
Positive selection and intrinsic disorder are associated with multifunctional C4(AC4) proteins and geminivirus diversification
It is suggested that non-synonymous mutations and mutations that increase the length of C4(AC4) drive protein diversity that is intrinsically disordered, which could explain C4/AC4 functional variation and contribute to both geminivirus diversification and host jumping.
Deeply Sequenced Infectious Clones of Key Cassava Begomovirus Isolates from Cameroon
We deeply sequenced two pairs of widely used infectious clones (4 plasmids) of the bipartite begomoviruses African cassava mosaic virus (ACMV) and East African cassava mosaic Cameroon virus (EACMCV).