The ABCB1-C3435T polymorphism likely acts as a risk factor for resistance to antiepileptic drugs

@article{Li2014TheAP,
  title={The ABCB1-C3435T polymorphism likely acts as a risk factor for resistance to antiepileptic drugs},
  author={Minzhi Li and Jinjing Tan and Xiaoqing Yang and Li Su and Lian Gu},
  journal={Epilepsy Research},
  year={2014},
  volume={108},
  pages={1052-1067}
}
Previous studies have attempted to confirm the association between the ABCB1-C3435T polymorphism and drug-resistant epilepsy and produced discordant findings. A meta-analysis was conducted to assess the role of the C3435T polymorphism in drug-resistance in epilepsy. Databases were obtained from PubMed, Embase, the Chinese Wanfang, CNKI, and Chongqing VIP database, and all relevant studies were compiled up to February 2013. Odds ratios (ORs) were calculated using models of both fixed- and random… CONTINUE READING
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