The A370T variant (StuI polymorphism) in the LDL receptor gene is not associated with plasma lipid levels or cardiovascular risk in UK men.

Abstract

Over 800 different missense mutations in the low density lipoprotein (LDL) receptor gene (LDLR) have been identified in patients with familial hypercholesterolaemia (FH). Only two of them, including the Alanine to Threonine change at position 370 (A370T), have been discovered in FH patients but do not cause FH. The frequency of the 370T allele has been… (More)

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Cite this paper

@article{Vieira2006TheAV, title={The A370T variant (StuI polymorphism) in the LDL receptor gene is not associated with plasma lipid levels or cardiovascular risk in UK men.}, author={Jos{\'e} Ricardo Dos Santos Vieira and Ros A. Whittall and J W Astley Cooper and George J. Miller and Steve E Humphries}, journal={Annals of human genetics}, year={2006}, volume={70 Pt 6}, pages={697-704} }