The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells.

@article{Ramkumar1993TheAA,
  title={The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells.},
  author={Vickram Ramkumar and Gary L. Stiles and Michael A. Beaven and H. Sheik Jahabar Ali},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 23},
  pages={16887-90}
}
Mast cells release the mediators of the immediate hypersensitivity reaction. Adenosine is known to modulate this process, but the receptor responsible for this is not the classical A1 or A2 adenosine receptors. This study was undertaken to determine whether the unique adenosine receptor (AR) previously postulated in a cultured mast cell line (RBL-2H3 cells… CONTINUE READING