The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.

@article{Mindrinos1994TheAT,
  title={The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.},
  author={Michael Mindrinos and Fumiaki Katagiri and G L Yu and Frederick M. Ausubel},
  journal={Cell},
  year={1994},
  volume={78 6},
  pages={1089-99}
}
In plants, resistance to a pathogen is frequently correlated with a genetically defined interaction between a plant resistance gene and a corresponding pathogen avirulence gene. A simple model explains these gene-for-gene interactions: avirulence gene products generate signals (ligands), and resistance genes encode cognate receptors. The A. thaliana RPS2 gene confers resistance to the bacterial pathogen P. syringae carrying the avirulence gene avrRpt2. A map-based positional cloning strategy… CONTINUE READING
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