The 8p12 myeloproliferative disorder. t(8;19)(p12;q13.3): a novel translocation involving the FGFR1 gene.

@article{Mugneret2000The8M,
  title={The 8p12 myeloproliferative disorder. t(8;19)(p12;q13.3): a novel translocation involving the FGFR1 gene.},
  author={Francine Mugneret and Max Chaffanet and Marck Maynadi{\'e} and G{\'e}raldine Guasch and Bernardine Favre and Olivier Casasnovas and Daniel Birnbaum and Marie Jos{\`e}phe P{\'e}busque},
  journal={British journal of haematology},
  year={2000},
  volume={111 2},
  pages={647-9}
}
Translocations affecting the chromosomal locus 8p12 are hallmarks of an atypical stem cell myeloproliferative disorder. These events disrupt the fibroblast growth factor receptor 1 (FGFR1) gene and fuse the FGFR1 C-terminus catalytic domain with unrelated proteins. Here, we report on the characterization of the 19q13.3 locus as the fifth FGFR1 chromosomal partner.