The 8-silyloxyquinoline scaffold as a versatile platform for the sensitive detection of aqueous fluoride.

  title={The 8-silyloxyquinoline scaffold as a versatile platform for the sensitive detection of aqueous fluoride.},
  author={Xinqi Zhou and Rui Lai and Hui Li and Cliff I. Stains},
  journal={Analytical chemistry},
  volume={87 8},
Utilizing a novel 8-silyloxyquinoline scaffold, we demonstrate the ability to synthesize fluorogenic probes for the sensitive and selective detection of inorganic fluoride (NaF) in aqueous samples. Our initial probe design (2) is capable of detecting inorganic fluoride at levels as low as 3.8 μM (72 ppb) in aqueous solutions, well below PHS recommended levels for drinking water (0.7-1.2 ppm), placing this probe among the most sensitive fluoride sensors reported to date. Furthermore, our results… Expand
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