The 70-kDa heat shock proteins associate with glandular intermediate filaments in an ATP-dependent manner.

@article{Liao1995The7H,
  title={The 70-kDa heat shock proteins associate with glandular intermediate filaments in an ATP-dependent manner.},
  author={Jian Liao and L A Lowthert and Nafisa Ghori and Moutasem Omary},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 2},
  pages={
          915-22
        }
}
Keratin polypeptides 8 and 18 (K8/18) are intermediate filament proteins expressed preferentially in glandular epithelia. We describe the identification, by co-immunoprecipitation from normal human colonic tissues and cultured cell lines, of the 70-kDa heat shock protein (hsp) and its related heat shock cognate protein as K8/18-associated proteins (hsp/c). The association is significant but sub-stoichiometric and occurs preferentially with the soluble rather than the cytoskeletal K8/18… CONTINUE READING
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