The 65,000-Mr DNA-binding and virion trans-inducing proteins of herpes simplex virus type 1.

@article{Marsden1987The6D,
  title={The 65,000-Mr DNA-binding and virion trans-inducing proteins of herpes simplex virus type 1.},
  author={Howard S. Marsden and Mary E. Campbell and Lars Haarr and Margaret C Frame and Deborah S. Parris and Mary Murphy and R Graham Hope and M. T. Muller and Chris Preston},
  journal={Journal of virology},
  year={1987},
  volume={61 8},
  pages={2428-37}
}
The possible identity of the herpes simplex virus type 1 (HSV-1) 65K (65,000-Mr) virion protein which stimulates transcription from immediate-early genes with the HSV-1 65K DNA-binding protein was investigated. The two proteins were found to be distinct by the three separate criteria of immunological reactivity, tryptic peptide fingerprinting, and mobility in two-dimensional gels. Using HSV-1/HSV-2 intertypic recombinants and a serotype-specific antiserum, we located the gene encoding the 65K… CONTINUE READING

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