The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives

@article{Fur1984The5P,
  title={The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives},
  author={G. Le Fur and F. Imbault and N. Mitrani and F Marquis and Christian Renault and Marie Christine Dubroeucq and Claude Gueremy and Andr{\'e} Uzan},
  journal={Neuropharmacology},
  year={1984},
  volume={23},
  pages={169-173}
}
View on Elsevier
doi.org
6 Citations

6 Citations

Citation Type

Citation Type

Differential Interaction of Phencyclidine‐Like Drugs with the Dopamine Uptake Complex In Vivo
TLDR
The results imply that the pharmacological effects of PCP are due to its simultaneous interaction with the dopamine uptake complex and the PCP receptor, and TCP and MK‐801, which have the same behavioral properties as PCP, exert their action only through the interaction withThe PCP receptors.
Pharmacokinetics and bioavailability of viqualine a new antidepressant
SummaryA high performance liquid chromatographic assay was developed for plasma and urine levels measurement of viqualine. The assay was used to study the disposition of 25 mg intravenous and oral…
Quantitative Autoradiography of [3H]Indalpine Binding Sites in the Rat Brain: I. Pharmacological Characterization
TLDR
Electrolytic lesions of the dorsal raphe or medial forebrain bundle, which cause a degeneration of 5‐HT cell bodies and fibers, respectively, resulted in a 30–40% reduction in the binding of [3H]indalpine.
The radiosynthesis of nca [O‐methyl‐11C]viqualine, through an N‐trityl‐protected intermediate, as a potential pet radioligand for 5HT re‐uptake sites
Viqualine, {4-[3-[3(R)-ethenyl-4(R)-piperidinyl]propyl]-6-methoxyquinoline}, has been labelled in the O-methyl position with no-carrier-added (nca) carbon-11 (t1/2 = 20.4 min; β+ = 99.8%) to provide…
Influence of GM1 gangliosides on the growth of cultured rat embryonic serotonergic neurons
Isomérisation cis‐trans en Série Alkyl‐4‐vinyl‐3‐pipéridine par Sigmatropie [3.3]. Synthèse des Epivinyl Isomères des Alcaloïdes du Quinquina
cis, trans Isomerization of 4-Alkyl-3-vinylpiperidines by [3.3] Sigmatropic Rearrangement. Synthesis of Epivinyl Isomers of Cinchona Alkaloids Isomerization of 4-alkyl-3-vinylpiperidines…

References

SHOWING 1-10 OF 15 REFERENCES
Effects of 4-(3-indolyl-alkyl)piperidine derivatives on uptake and release of noradrenaline, dopamine and 5-hydroxytryptamine in rat brain synaptosomes, rat heart and human blood platelets.
Comparative action of fenfluramine on the uptake and release of serotonin and dopamine.
Effect of monoamine liberators on the metabolism of 5-hydroxytryptamine in blood platelets.
Effects of the d- and l-isomers of amphetamine on uptake, release and catabolism of norepinephrine, dopamine and 5-hydroxytryptamine in several regions of rat brain.
Monoamine oxidase inhibitory properties of 5‐hydroxymethyl‐3‐m‐tolyloxazolidin‐2‐one (toloxatone)
TLDR
This paper reports on the monoamine oxidase inhibiting properties in virro and in vivo, of a new oxazolidin-2-one derivative with antidepressant activity in animals and potential clinical efficacy in man.
Two sites of 5-hydroxytryptamine uptake in blood platelets.
The importance of neuronal uptake of amines for amphetamine-induced release of 3H-norepinephrine from isolated brain tissue.
TLDR
The results indicate that amphetamine is transported by the neuronal uptake system and that cocaine and desipramine inhibit the release of 3 H-norepinephrine at low concentrations of amphetamine by inhibiting the transport of Amphetamine into the neuron.
Effects of reserpine and imipramine on vesicular serotonin uptake and storage in intact human platelets.
d-Amphetamine as a releaser or reuptake inhibitor of biogenic amines in synaptosomes.
Platelet 5-HT uptake and release stopped rapidly by formaldehyde
TLDR
The treatment of platelets with formaldehyde is described, which seems to provide a tool for precise studies of the kinetics of uptake and release of 5-hydroxytryptamine.
...
...