The 5-HTTLPR polymorphism of the serotonin transporter gene and short term behavioral response to methylphenidate in children with ADHD

@inproceedings{Thakur2010The5P,
  title={The 5-HTTLPR polymorphism of the serotonin transporter gene and short term behavioral response to methylphenidate in children with ADHD},
  author={Geeta A. Thakur and Natalie Grizenko and Sarojini M. Sengupta and Norbert Schmitz and Ridha Joober},
  booktitle={BMC psychiatry},
  year={2010}
}
BACKGROUND Animal models of ADHD suggest that the paradoxical calming effect of methylphenidate on motor activity could be mediated through its action on serotonin transmission. In this study, we have investigated the relationship between the 5-HTTLPR polymorphism in the serotonin transporter gene (SLC6A4) and the response of ADHD relevant behaviors with methylphenidate treatment. METHODS Patients between ages 6-12 (n = 157) were assessed with regard to their behavioral response to… CONTINUE READING
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SAS System for Mixed Models 2nd edition

  • RC Littell, GA Milliken, WW Stroup, RD Wolfinger
  • SAS Institute Inc;
  • 2006

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