The 5-HTTLPR polymorphism in South African healthy populations: a global comparison

@article{Esau2007The5P,
  title={The 5-HTTLPR polymorphism in South African healthy populations: a global comparison},
  author={Luke Esau and Mandeep Kaur and Lucinda Adonis and Zainunisha Arieff},
  journal={Journal of Neural Transmission},
  year={2007},
  volume={115},
  pages={755-760}
}
The serotonin transporter promoter length polymorphism (5-hydroxytryptamine transporter length polymorphism, 5-HTTLPR) in serotonin transporter gene has been implicated in numerous psychiatric disorders. Having a high affinity for the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT), serotonin transporter controls the duration, availability and signaling capacity of 5-HT in the synapse. Association studies have focused extensively on this polymorphic region as the frequencies of long- and… CONTINUE READING
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