The 5' repeat elements of the mouse Xist gene inhibit the transcription of X-linked genes.

Abstract

X chromosome inactivation in mammals requires the Xist gene, which is exclusively expressed from the inactive X chromosome (Xi). The large heterogeneous Xist nuclear RNA colocalizes with Xi, most likely through nuclear protein interactions. The 5' region of the Xist RNA contains a series of well-conserved tandem repeats known to bind heteronuclear proteins… (More)

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@article{AllamanPillet2000The5R, title={The 5' repeat elements of the mouse Xist gene inhibit the transcription of X-linked genes.}, author={Nathalie Allaman-Pillet and A Djema{\"i} and Corinne Bonny and Daniel F. Schorderet}, journal={Gene expression}, year={2000}, volume={9 3}, pages={93-101} }