The 4,5-double bond of ceramide regulates its dipole potential, elastic properties, and packing behavior.

Abstract

The biological activities of ceramides show a large variation with small changes in molecular structure. To help understand how the structure regulates the activity of this important lipid second messenger, we investigated the interfacial features of a series of synthetic ceramide analogs in monomolecular films at the argon-buffer interface. To minimize… (More)

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