The 30-bp deletion of Epstein-Barr virus latent membrane protein-1 gene has no effect in nasopharyngeal carcinoma.

@article{Chang2006The3D,
  title={The 30-bp deletion of Epstein-Barr virus latent membrane protein-1 gene has no effect in nasopharyngeal carcinoma.},
  author={Kai-Ping Chang and Sheng-po Hao and Shinn-Yn Lin and S. W.-N. Ueng and P Pai and Chen-kan Tseng and Chuen Hsueh and Meng-Shu Hsieh and J S Yu and N N Tsang},
  journal={The Laryngoscope},
  year={2006},
  volume={116 4},
  pages={541-6}
}
OBJECTIVE The specific 30-bp deletion of the Epstein-Barr virus (EBV)-derived latent membrane protein-1 gene has been suggested to be associated with the pathogenesis of nasopharyngeal carcinoma (NPC) and a more aggressive phenotype of some EBV-associated malignancies. METHODS The authors conducted a retrospective cohort study. Between 1995 and 2001, 542 patients who had received complete courses of radiotherapy followed by at least 3 years of follow up were enrolled. Patients were divided… CONTINUE READING

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