The 24th Meeting of the Society for Glycobiology was held in Boston, Massachusetts from 23–26 November 1996. The chairman of the organizing committee was Dr Vernon Reinhold.

Abstract

The meeting was initiated on Saturday evening with a Plenary Lecture by S. Kornfeld on the Regulation of Mannose Phosphorylation of Lysosomal and Secretory Glycoproteins. He presented the results of his intensive research on the substrate specificity of the committed enzyme, the GlcNAc-P transferase, which synthesizes the recognition marker directing lysosomal enzymes to their proper intracellular compartment. It is now apparent that the substrate recognition site for the GlcNAc-P transferase is quite complex and involves far more than primary peptide sequence. The substrate recognition site appears to involve a large portion of the lysosomal enzyme surface, but exact details of the complete substrate recognition site have yet to be resolved. Each morning session then began with two Perspective Lectures followed by Salient Topic Symposia. The Perspective lecture speakers included P. Robbins on Oligosaccharide Signaling, D. Harn on Oligosaccharide Modulation of the Immune Response, H.P. Hauri on Golgi Recycling Pathways, D. Williams on Calnexin, R. Jefferis on The Effects of Antibody Glycosylation and M. Brenner on Antigen-specific Recognition of Glycolipids by T lymphocytes. The Salient Topics covered a wide range of subject matter from control of glycosyltransferase gene expression and localization (N. Shaper, K. Colley), early processing pathways of N-linked oligosaccharides (R. Spiro), the functions of glycolipids and glycosylphosphatidylinositol (GPI) anchors (C. Lingwood, T. Seyfried, M. Ferguson), therapeutic glycoconjugates, inhibitors of carbohydrate function and bacterial binding to carbohydrate receptors (E. Tuomanen, L. Kiessling), carbohydrates and glycosyltransferases modulating cell adhesion (I. Stamenkovic, S. Hakomori, J. Lowe) and the role of sugars on IgG (R. Dwek). The wide range of topics and large number of speakers precludes a detailed description of each talk; the overall theme was generally directed to demonstrating the importance of carbohydrates as recognition markers for biological processes. The Perspective Lectures were then followed by a number of symposia on specific topics including; biosynthesis of proteoglycans, glycosylation of proteins in insect cells,

DOI: 10.1023/A:1018513332240

Cite this paper

@article{Schutzbach2004The2M, title={The 24th Meeting of the Society for Glycobiology was held in Boston, Massachusetts from 23–26 November 1996. The chairman of the organizing committee was Dr Vernon Reinhold.}, author={John S. Schutzbach and Inka Brockhausen}, journal={Glycoconjugate Journal}, year={2004}, volume={14}, pages={697-698} }