The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily.

@article{Illing1997The2R,
  title={The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily.},
  author={Michelle Illing and Laurie L. Molday and Robert S Molday},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 15},
  pages={10303-10}
}
Outer segments of mammalian rod photoreceptor cells contain an abundantly expressed membrane protein that migrates with an apparent molecular mass of 220 kDa by SDS-gel electrophoresis. We have purified the bovine protein by immunoaffinity chromatography, determined its primary structure by cDNA cloning and direct peptide sequence analysis, and mapped its distribution in photoreceptors by immunocytochemical and biochemical methods. The full-length cDNA encodes a 2280-amino acid protein… CONTINUE READING

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