The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts.

@article{Staskus1991The2P,
  title={The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts.},
  author={P W Staskus and Frank R. Masiarz and Leo Pallanck and Susan P Hawkes},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 1},
  pages={449-54}
}
We report the electrophoretic purification and characterization of the 21-kDa protein, an extracellular matrix component synthesized during the early stages of transformation of chicken embryo fibroblasts infected with Rous sarcoma virus (Blenis, J., and Hawkes, S. P. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 770-774; Blenis, J., and Hawkes, S. P. (1984) J. Biol. Chem. 259, 11563-11570). The NH2-terminal amino acid sequence of the protein is greater than 60% identical to a consensus sequence… CONTINUE READING

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