The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.
@article{Arber2016The2R, title={The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.}, author={D. Arber and A. Orazi and R. Hasserjian and J. Thiele and M. Borowitz and M. L. Le Beau and C. Bloomfield and M. Cazzola and J. Vardiman}, journal={Blood}, year={2016}, volume={127 20}, pages={ 2391-405 } }
The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues was last updated in 2008. [...] Key Method The revisions to the categories of myeloid neoplasms and acute leukemia will be published in a monograph in 2016 and reflect a consensus of opinion of hematopathologists, hematologists, oncologists, and geneticists. The 2016 edition represents a revision of the prior classification rather than an entirely new classification and attempts to incorporate new clinical…Expand Abstract
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References
SHOWING 1-10 OF 167 REFERENCES
Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system.
- Medicine
- Blood
- 2009
- 139
- PDF
Significance of FAB subclassification of "acute myeloid leukemia, NOS" in the 2008 WHO classification: analysis of 5848 newly diagnosed patients.
- Medicine
- Blood
- 2013
- 88
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.
- Medicine
- Blood
- 2009
- 3,841
- PDF
Chronic myeloid leukemia: 2014 update on diagnosis, monitoring, and management
- Medicine
- American journal of hematology
- 2014
- 173
Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification.
- Medicine
- Blood
- 2010
- 89
Reproducibility of the WHO histological criteria for the diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms
- Medicine
- Modern Pathology
- 2014
- 34
- PDF
The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features
- Medicine
- Leukemia
- 2008
- 152
- PDF
Should myeloid and lymphoid neoplasms with PCM1‐JAK2 and other rearrangements of JAK2 be recognized as specific entities?
- Biology, Medicine
- British journal of haematology
- 2014
- 46
Revised international prognostic scoring system for myelodysplastic syndromes.
- Medicine
- Blood
- 2012
- 1,646
- PDF
Pediatric myelodysplasia: a study of 68 children and a new prognostic scoring system.
- Medicine
- Blood
- 1995
- 209
- PDF